Conformal coating certainly wouldn't hurt, although we never bothered.
Shock/Vibration is relatively easy - secure everything. In another life I pre-qualified - I think it was eight - identical systems for NASA. The through hole components had to be staked in place with some kind of glue.
In general, bolt down or otherwise secure connectors if you're worried about them coming apart - that's why Jeep used those annoying little latches everywhere. Don't rely on PC grade connectors to stay in place without help. Blah, blah, blah.
What about where the wires connect to the board? They'll be soldered in, then fed through a hole in the enclosure wall where there will be a strain relief, but I probably need to glue the wires down within some distance of the solder joint to keep it from fatigue cracking, yes? Or is an inch or two of wire small enough to not be a concern?
In my industry everything is either screw terminals or crimped connectors. I know just enough here to overthink without knowing when I'm overthinking.
