Just to be clear, the sidewall failure I am referring to is not anything immediate, it is the cumulative effect that can result in a failure much later, even a year or more later. Most people wouldn't even connect the two. For example, once a highway tire has been run low for a while it is advised by tire experts to replace it as it has suffered irreversible sidewall weakening which can lead to separation and failure down the road.
After having a sudden and catastrophic failure years ago on the front an F250 at highway speed I tend to error on the extreme side of caution, that's something you never forget.
There is a blog by a forensic tire engineer named Roger Marble and although a lot of it has to do with RVs there is a lot of information that pertains to every tire and use scenario. During his career he did forensic studies on failed tires and almost every early/sudden failure could be traced to a period of running low at some point during the tire's life.
the friction generated will grow with the square of speed, so cutting speed in half will cut the tire heat by 75%. If I was worried, I could hit mine with an IR gun after a 70mph run on the highway at 25 psi and then compare it at a later time after doing 40-50mph at 10psi, but my entirely gut-based feeling based on no data whatsoever is that a few minutes at 45mph and 10psi does not result in a hotter tire than 70mph at 25psi (or said another way, the reduction in speed has a bigger impact than the lower pressure).
Now, I've thought about how bad it would be to have a 35" tire blow out on something with a 103" wheelbase and 'm not ballsy enough to run aired down at 70 for any period of time. But some people are and the vast majority seem to have lived to tell about it.
I see the bigger risk as when people just don't pay attention to their tire pressure and they daily-drive for months on end with a visibly low tire. Think about how much more seldom we hear about blowouts since the advent of TPMS.
